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Basalioma, or basal cell carcinoma, is one of the types of malignant neoplasms of the skin that develops from atypical cells of the basal layer of the epidermis. Due to the basal cells, other layers of the skin are updated - new cells are formed from them as Cialis Tadalafil ones die. Basalioma refers to non-melanoma types of skin cancer, that is, it does not develop from melanocytes (skin cells that produce melanin pigment). Why cancer develops, in particular on the skin, cannot be said for sure. It is known that the transformation of a cell from benign to malignant occurs as a result of a number of disorders in its genome. A group of adverse factors has also been identified that, individually or in combination, affect the development of carcinoma (cancer) of the skin.

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Small translucent lumps. They are localized on the skin of the face and neck. May bleed if damaged. Wax growth. Cancer develops as white scarring on the skin, usually on and around the face. Lesions are usually painless, slightly waxy in appearance, and raised, but without a well-defined border. The skin in and around the affected area may appear tight and shiny. Open sores. In some cases, an open wound that does not heal is an early sign of basal cell carcinoma. Ulcers can bleed for up to several weeks before crusting over and then reopening and bleeding. An open wound, no matter how small, needs attention.

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To protect the body from the influence of harmful factors (insolation, chemical carcinogens, etc.), natural recovery mechanisms work in the skin. When "breakdowns" occur in the DNA of a cell, the body's defenses try to repair them. If this fails, the mechanism of programmed cell death, apoptosis, is triggered.

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  • Imaging
  • What is a basalioma (basal cell carcinoma)
  • Sometimes suppressor genes are damaged, which are responsible for preventing the development of malignant neoplasms.
  • For example, the Fas ligand (FasL) gene normally controls that healthy cells do not turn into cancer cells, it also triggers the destruction of defective cells.
  • However, with constant exposure to the skin of harmful factors, the activity of this gene decreases and it copes worse with its functions.
  • Classification and stages of development of basalioma.
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Classification of basal cell carcinoma according to clinical manifestations: Nodular (nodular) form. It is considered "classic" and accounts for three-quarters of all cases of basalioma. The formation can be of different sizes (from a few millimeters to 2-3 cm), waxy or translucent in color, interspersed with red and blue dots (vascular "asterisks"). It is slow growing and most often occurs on the head or neck. The ulcerative manifestation of basalioma can be considered as a result of the natural development of the nodular variant. The growth of tumor cells in the central zone leads to the destruction of the tumor focus with the formation of an ulcer.

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It is a spot covered with purulent-necrotic crusts. As a rule, the ulcerative form is an advanced stage of skin cancer. Superficial basalioma has gentle insedge-shaped edges, it can be of various shades of red. It can exist on the human body for decades, since it is localized in areas less prone to insolation (very rarely on the face), and does not cause discomfort. Characterized by slow growth Flat basalioma, or scleroderma-like basal cell carcinoma, is characterized by an aggressive course with possible growth into soft tissues.

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This form rarely bleeds and practically does not ulcerate. Symptoms may resemble psoriasis or eczema. The infiltrative form is associated with the progression of nodular and flat forms of cancer. This variant is characterized by a high risk of rapid development in depth, metastasis and a tendency to relapse after treatment.